ACTH 1-34

ACTH 1-34 is a synthetic peptide corresponding to the first 34 amino acids of adrenocorticotropic hormone (ACTH). It represents an N-terminal fragment of the full 39-residue hormone and is widely used as a peptide reference standard. It is supplied strictly as laboratory research material for research use only.

Research Background

ACTH 1-34 has been studied in the context of the melanocortin receptor system, and in particular pathways associated with the MC2 receptor and the hypothalamic-pituitary-adrenal (HPA) axis. As a defined fragment of the parent hormone, it is used in in vitro research to examine how sequence length relates to receptor engagement, providing a comparator to the shorter ACTH 1-24 fragment and the full-length peptide.

Within endocrinology-focused laboratory research, ACTH 1-34 serves as a tool compound for investigating melanocortin signalling and steroidogenic-pathway biology in model systems. Its role is that of a characterised research standard rather than any applied use, and interest centres on structure-activity relationships across the ACTH fragment series.

ACTH 1-34 Specifications & Handling

• Purity: ≥99% by analytical determination.
• Analytical verification: third-party reversed-phase HPLC and mass spectrometry, with a batch certificate of analysis (COA) available.
• Classification: N-terminal 34-residue fragment of adrenocorticotropic hormone (ACTH).
• Physical form: lyophilised powder.
• Storage: store cool and dark; keep the lyophilised material sealed and shielded from light and moisture.
• Reconstitution: reconstitute with bacteriostatic water or a suitable research-grade solvent where applicable, at assay-appropriate concentrations.
• Use restriction: laboratory research use only; not for human or veterinary use.

Related Research Compounds

Researchers studying peptide-hormone and receptor systems may also reference Gonadorelin, Triptorelin (GnRH) and Sermorelin / Ipamorelin blend as related endocrine-research peptides. Explore additional standards in the research peptides category.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.