Sermorelin + Ipamorelin Blend

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Sermorelin + Ipamorelin are two synthetic peptides known for their interaction with growth hormone regulatory pathways.

Sermorelin is a synthetic analog of growth hormone–releasing hormone (GHRH), specifically representing the first 29 amino acids of the endogenous GHRH sequence. Ipamorelin is a synthetic pentapeptide that functions as a selective agonist of the growth hormone secretagogue receptor (GHSR).

Available Research Variants

This research compound is offered by PureRawz. Researchers may select from the following formulations:

  • 10 mg – 5 mg Sermorelin + 5 mg Ipamorelin
  • 20 mg – 10 mg Sermorelin + 10 mg Ipamorelin

Take note that each formulation is intended solely for controlled laboratory investigation.

PropertySermorelinIpamorelin
IUPACL-tyrosyl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-asparagyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-glycyl-L-glutaminyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-isoleucyl-L-methionyl-L-seryl-L-argininamide(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Molecular FormulaC149H246N44O42SC38H49N9O5
Molecular Weight 3357.9 g/mol 711.9 g/mol
Chemical ClassGHRH Analog PeptideGrowth Hormone Secretagogue
Synonyms
  • SERMORELIN
  • Sermorelina
  • 86168-78-7
  • Sermoreline
  • Sermorelinum
  • Ipamorelin
  • 170851-70-4
  • NNC-26-0161
  • Y9M3S784Z6
  • Aib-His-D-2-Nal-D-Phe-Lys-NH2

Research Applications of Sermorelin + Ipamorelin

The combination of Sermorelin and Ipamorelin has been studied with the following:

Growth Hormone Regulation Studies

It may analyze the biological mechanisms involved in growth hormone secretion. The two compounds interact with different receptors that regulate growth hormone release from the pituitary gland.

Metabolic Signaling Research

Experimental models may explore how growth hormone signaling influences metabolic processes such as energy utilization, cellular growth regulation, and lipid metabolism.

Tissue Regeneration and Repair Models

Some preclinical models analyze the relationship between growth hormone signaling and cellular regeneration pathways. These studies may examine interactions with growth factors involved in tissue maintenance and repair.

Neuroendocrine Research

The interaction between ghrelin receptors, hypothalamic signaling, and pituitary hormone regulation is also investigated in neuroendocrine studies.

These research areas remain under investigation and require additional controlled studies to better understand the biological mechanisms involved.

Working Mechanism

Sermorelin and Ipamorelin influence growth hormone signaling through distinct but complementary receptor pathways.

Sermorelin functions as an analog of natural growth hormone–releasing hormone. In experimental models, it binds to GHRH receptors located in the anterior pituitary gland, which may stimulate signaling pathways associated with pulsatile growth hormone release.

Ipamorelin acts as a selective agonist of the growth hormone secretagogue receptor (GHSR), also known as the ghrelin receptor. Activation of this receptor can stimulate intracellular signaling pathways involved in growth hormone secretion.

Combined Pathway Interaction

When studied together, Sermorelin and Ipamorelin may influence two different regulatory systems involved in growth hormone signaling:

  • GHRH receptor activation (Sermorelin)
  • Ghrelin receptor activation (Ipamorelin)

This dual-pathway interaction is a subject of interest in experimental endocrine research.

Why Buy at PureRawz

All compounds distributed by PureRawz are supplied exclusively for scientific and research purposes. Aside from it. PureRawz offers trustworthy research compounds by providing Certificates of Analysis (COA) for the blended research compound. They also offer free shipping for orders above 100$.

For more information about Sermorelin + Ipamorelin, you may reach out to  support@purerawz.co.

Research Disclaimer

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY and not for veterinary or human use.

The compound must be handled only by qualified professionals in controlled research environments. All studies should follow appropriate institutional research standards, including oversight from Institutional Review Boards (IRB) or Institutional Animal Care and Use Committees (IACUC) where applicable.

Researchers are responsible for complying with all regulations governing laboratory chemicals and research material.

Frequently Asked Questions

What is the Sermorelin + Ipamorelin Blend?

This is a research blend combining the peptides Sermorelin and Ipamorelin in a single reference preparation. PureRawz Australia supplies the blend for in vitro and non-clinical laboratory investigation only.

Is the Sermorelin + Ipamorelin Blend legal or approved in Australia?

The blend is not an approved therapeutic good and its component peptides are not registered on the Australian Register of Therapeutic Goods for any use. It is offered for laboratory research use only, with the researcher responsible for TGA and Australian legal compliance.

How is the Sermorelin + Ipamorelin Blend tested?

Each batch is analysed by third-party laboratories using HPLC and mass spectrometry to confirm the identity of its components and overall purity. A batch certificate of analysis (COA) reflecting purity of at least 99% is available for reference.

How should the Sermorelin + Ipamorelin Blend be stored in a research setting?

As a lyophilised peptide blend, it is generally stored frozen and shielded from light and moisture to preserve the stability of both components. Once reconstituted it is typically held refrigerated and used within a short period per laboratory protocols.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.

Form

Peptide, Nasal Spray

Strength

10mg, 20mg, 200mcg per spray/20mg

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