Gonadorelin Acetate Nasal Spray

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Gonadorelin Acetate is a synthetic analog of gonadotropin-releasing hormone (GnRH), which is a naturally occurring decapeptide normally produced by the hypothalamus. In biological systems, GnRH plays a central role in regulating reproductive hormone signaling. It interacts with the pituitary gland and triggers the release of two key hormones: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are involved in reproductive hormone regulation and related physiological processes.

Gonadorelin acetate is studied for its role in the hypothalamic-pituitary-gonadal (HPG) axis and hormone signaling pathways in research models. It can be beneficial for investigating endocrine feedback mechanisms, reproductive hormone regulation, and GnRH-related biological activity in laboratory models.

Note: At PureRawz, Gonadorelin Acetate comes as a nasal spray. 20 mcg per spray (2 mg per bottle).

Chemical Properties of Gonadorelin Acetate

PropertyInformation
CAS Number34973-08-5
Molecular FormulaC57H79N17O15
Molecular Mass1242.3 g/mol
SynonymsGonadorelin acetate, ABBOTT-41070, GONAbreed, 2RG1XQ1NYJ
IUPAC Nameacetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Storage2-8°C (36-46°F)

How Does Gonadorelin Acetate Work?

Gonadorelin acetate functions as a synthetic analog of GnRH. It interacts with GnRH receptors located on the anterior pituitary gland. This interaction stimulates the release of two key gonadotropins, LH and FSH, in research models. These hormones subsequently influence gonadal activity and regulate the production of reproductive hormones such as testosterone and estrogen.

Because of this upstream signaling role, gonadorelin acetate is used in research to investigate hormonal signaling pathways and pituitary responses. It is also studied to better understand regulatory mechanisms within the hypothalamic-pituitary-gonadal (HPG) axis.

Research Findings on Gonadorelin Acetate

Gonadorelin Acetate has been studied in scientific and clinical research.Here are some areas where it is often used in research:

In a controlled aquatic research model, gonadorelin administration altered endocrine profiles by increasing circulating sex steroids such as estradiol, progesterone, and testosterone. It also promoted final oocyte maturation and ovulation compared with untreated research models. These findings shows gonadorelin’s ability to modulate gonadotropin‑driven reproductive processes in vertebrate endocrine research.

In a mammalian research model, administration of gonadorelin at specific doses induced ovulation of persistent ovarian follicles. It also initiated a new follicular wave, demonstrating a dose-dependent effect on follicular dynamics and pituitary-gonadal signaling pathways.

Note: Gonadorelin was previously approved by the FDA for certain diagnostic and clinical applications. However, no actively marketed FDA-approved gonadorelin products are currently available. This compound is now supplied by PureRwaz for research purposes only.

Where to Buy Gonadorelin Acetate Nasal Spray?

PureRawz provides high-purity Gonadorelin Acetate Nasal Spray for laboratory and research applications. The compound is  prepared to ensure consistent performance in experimental studies of hormone signaling and pituitary-gonadal regulation.

All the products undergoes rigorous quality control and is accompanied by an independent Certificate of Analysis (COA). This verification confirms the compound’s identity, purity, and overall quality.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human usage.

Frequently Asked Questions

What is Gonadorelin Acetate Nasal Spray?

Gonadorelin Acetate is a synthetic decapeptide corresponding to gonadotropin-releasing hormone (GnRH), supplied here as a research nasal-spray format. This product is intended for laboratory research use only and is not for human or veterinary use.

Is Gonadorelin Acetate Nasal Spray legal or approved in Australia?

Gonadorelin Acetate Nasal Spray is not an approved therapeutic good in Australia and is supplied strictly for laboratory research use only. The researcher is solely responsible for compliance with all applicable TGA regulations and Australian laws.

How is Gonadorelin Acetate Nasal Spray tested?

Each batch is analysed by third-party laboratories using high-performance liquid chromatography (HPLC) and mass spectrometry to confirm identity and purity of at least 99%. A batch-specific Certificate of Analysis (COA) is available for reference.

How should Gonadorelin Acetate Nasal Spray be stored for research?

For research handling, the nasal-spray format is generally kept refrigerated and protected from light and heat to help preserve peptide integrity. Storage conditions should follow the guidance provided with the batch documentation.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.

Variant

20mcg per spray/2mg/10ml

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