Epithalon

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Epithalon is a synthetic tetrapeptide composed of four amino acids. It has attracted interest in scientific research related to cellular signaling, chromosomal stability, and peptide-mediated regulatory processes. This compound was developed to structurally resemble peptides associated with the pineal gland and is frequently examined in laboratory models investigating cellular regulation and peptide activity.

Chemical and Molecular Properties

PubChem CID	219042
Molecular Formula	C14H22N4O9
Molecular Weight	390.35 g/mol
Synonyms	Epithalone  AEDG Peptide (derived from the amino acid sequence Ala-Glu-Asp-Gly) Ala-Glu-Asp-Gly (Sequence)
IUPAC	(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
CAS	307297-39-8
Labeling	Research Use Only (RUO), not for human or animal consumption
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO)
Storage Temperature	Store at -20°C
Solubility	Water, DMSO (research-grade solvents)
Safety	Handle with gloves, a lab coat, eye protection; use a fume hood if dust/aerosol is possible

Mechanisms of Action

Epithalon has been examined in laboratory studies for its potential interaction with molecular pathways associated with chromosomal maintenance and cellular regulatory processes. In experimental models, the peptide has been investigated for its influence on telomerase-related activity, an enzyme system involved in maintaining the structural integrity of telomeres located at the ends of chromosomes.

Telomeres play an important role in protecting chromosomal DNA during repeated cellular division. Research has explored whether Epithalon may interact with regulatory mechanisms that influence telomerase expression and telomere-associated processes within controlled cellular environments.

Potential Research Applications

Epithalon is currently being studied in laboratory environments to better understand its biochemical characteristics and potential interactions with cellular signaling systems. Areas of research interest include:

Telomere and Chromosomal Stability Studies

Epithalon is investigated for its potential influence on telomerase-associated pathways and telomere maintenance mechanisms in experimental cellular models.

Cellular Stress Response Research

Researchers examine the peptide in studies evaluating cellular responses to oxidative conditions and redox-related biochemical pathways.

Pineal-Associated Signaling Studies

Experimental models have explored the peptide’s possible relationship with signaling mechanisms linked to pineal gland activity and circadian regulatory processes.

Peptide Signaling and Molecular Pathways

Epithalon is studied in laboratory assays focused on peptide-mediated cellular communication, intracellular signaling cascades, and regulatory protein activity.

Disclaimer

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For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.