Kp-10

Kp-10, also known as kisspeptin-10, is a decapeptide corresponding to the C-terminal fragment of kisspeptin, the peptide product of the KISS1 gene. It is classified as a kisspeptin-family signalling peptide and is offered strictly as a laboratory research reference material for neuroendocrine studies.

Research Background

Kp-10 has been investigated in the context of the hypothalamic-pituitary-gonadal axis. Research has examined its reported interaction with the KISS1R (GPR54) receptor and the studied role of kisspeptin signalling upstream of gonadotropin-releasing hormone neurons. As the shortest fully active fragment of kisspeptin, Kp-10 retains the receptor-binding region and is frequently used to explore the initiation of reproductive-axis signalling in model systems.

In laboratory work, Kp-10 serves as a reference tool for investigations of neuroendocrine regulation, GPCR pharmacology, and comparative kisspeptin research. Its compact structure and defined receptor affinity make it a common benchmark for studies of hypothalamic signalling cascades.

Kp-10 Specifications & Handling

• Purity: ≥99% by analytical testing.
• Verification: third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis (COA).
• Physical form: lyophilised powder.
• Storage: store cool and dark; refrigerate for short-term use and freeze for longer storage, protected from light and moisture.
• Reconstitution: bacteriostatic water is typically used to prepare working solutions for laboratory assays; prepare only what is required for immediate research use.

Related Research Compounds

Kp-10 is often studied alongside related kisspeptin and HPG-axis reference peptides such as Kp-102, Gonadorelin, and Triptorelin (GnRH). Explore the complete selection in our research peptides catalogue. This product is intended for laboratory research use only and is not for human or veterinary use.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.