Vinpocetine

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Vinpocetine is a semisynthetic derivative of the alkaloid vincamine, which is originally isolated from the periwinkle plant Vinca minor. In controlled laboratory environments, vinpocetine is investigated for its interactions with neuronal signaling pathways and its potential role in neurobiological research models.

Researchers study vinpocetine to better understand its influence on cellular signaling, oxidative processes, and vascular-related mechanisms in experimental systems. Due to these characteristics, the compound has attracted interest in studies focused on neuroprotection, cellular metabolism, and signal transduction pathways.

Chemical and Molecular Properties

PubChem CID	443955
Molecular Formula	C22H26N2O2
Molecular Weight	350.5 g/mol
Synonyms	Apovincaminic acid ethyl ester Ethyl apovincamin-22-oate Ethyl (+)-cis-apovincaminate cis-Apovincaminic acid ethyl ester Ethyl (+)-apovincaminate (3a,16a)-Eburnamenine-14-carboxylic acid ethyl ester Vinpocetinum
IUPAC	ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.02, 7.08, 18.015, 19]nonadeca-2,4,6,8(18),16-pentaene-17-carboxylate
CAS	42971-09-5
Labeling	Research Use Only (RUO), not for human or animal consumption
Chemical Structure Depiction
Purity	99% Purity
Classification	Research Use Only (RUO)
Storage Temperature	Store in room temperature of 25°C to 30°C (77°F to 86°F)

Mechanisms of Action

In laboratory models, vinpocetine has been investigated for its potential interaction with several cellular pathways associated with neuronal function.

One proposed mechanism involves inhibition of phosphodiesterase type 1 (PDE1). In experimental systems, PDE1 inhibition has been associated with increased intracellular levels of cyclic nucleotides such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), which may influence intracellular signaling activity.

Research models have also examined vinpocetine’s interaction with voltage-dependent sodium channels and its potential role in modulating calcium ion movement across cellular membranes. These mechanisms are studied in relation to neuronal excitability and signaling regulation.

Potential Research Applications

In controlled experimental settings, vinpocetine is explored to evaluate its effects on several biological and cellular processes.

Researchers investigate vinpocetine for:

Characterizing PDE1-related intracellular signaling pathways in laboratory models
Studying oxidative stress responses in neuronal cell research systems
Examining mechanisms associated with inflammatory signaling pathways, including NF-kB-related processes
Evaluating cellular energy metabolism and mitochondrial-associated activity in experimental environments
Investigating mechanisms related to vascular signaling and cerebral perfusion in controlled models

These investigations aim to further understand the compound’s biochemical interactions and cellular responses in research contexts.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Frequently Asked Questions

What is Vinpocetine?

Vinpocetine is a semi-synthetic derivative of vincamine, an alkaloid originally isolated from the periwinkle plant, studied for its vascular and cerebral research applications. It is supplied strictly as a research reference material and is not intended for human or veterinary use.

Can Vinpocetine be imported or is it legal in Australia?

Vinpocetine is provided solely for laboratory research use and is not supplied for human consumption. This class of compound may be subject to import and supply restrictions, so researchers must verify the current regulatory and import status in their jurisdiction before purchase.

How is Vinpocetine tested?

Identity and purity are confirmed by independent third-party analysis using HPLC combined with mass spectrometry. A batch-specific certificate of analysis (COA) documenting purity of at least 99% is provided.

How does Vinpocetine relate to Vincamine in research?

Vinpocetine is a semi-synthetic analogue derived from vincamine and is often studied alongside it as a structurally related reference compound. Comparative laboratory work commonly notes the derivation of vinpocetine from the parent vincamine alkaloid.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.