Nicotinamide Riboside

Nicotinamide Riboside (NR) is a pyridine-nucleoside form of vitamin B3 supplied strictly for laboratory research use only (not for human or veterinary use). It is classified within the NAD+ precursor family and is studied by Australian research laboratories as a reference compound in cellular energy metabolism and redox biology investigations.

Research Background

Nicotinamide Riboside is investigated as a substrate that enters the nicotinamide adenine dinucleotide (NAD+) biosynthetic salvage pathway. In cell-culture and biochemical models, researchers examine its phosphorylation by nicotinamide riboside kinases (NRK1 and NRK2) to nicotinamide mononucleotide, and the subsequent enzymatic conversion toward NAD+, a coenzyme central to oxidative metabolism.

Research interest also centres on NAD+-dependent enzyme systems, including sirtuins and poly(ADP-ribose) polymerases, which are studied in the context of mitochondrial function, DNA-repair signalling and cellular stress responses in vitro. These mechanistic studies use NR purely as a laboratory reference material for pathway characterisation.

Nicotinamide Riboside Specifications & Handling

• Purity: ≥99% as determined by analytical assay.
• Analytical verification: third-party HPLC and mass spectrometry, with a batch-specific Certificate of Analysis (COA) available.
• Physical form: crystalline solid or powder (batch dependent).
• Storage: keep in a sealed container, protected from light and moisture, stored cool and dry per generic laboratory practice; consult the COA for batch-specific guidance.
• Handling: use appropriate personal protective equipment and standard laboratory procedures for research chemicals.

Related Research Compounds

Laboratories characterising cofactor and metabolic pathways may also reference Uridine Monophosphate Disodium and Methylene Blue as complementary study materials, alongside Sulbutiamine. Browse the full range of research nootropics for related reference compounds. All materials are supplied for laboratory research use only, and researchers must confirm the regulatory and import status applicable in their own jurisdiction before ordering.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.