Galantamine Hydrobromide

AUD57

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Galantamine Hydrobromide is a quaternary ammonium salt derived from galantamine, an alkaloid originally isolated from plants in the Amaryllidaceae family, including Galanthus (snowdrop) species. While the compound was first identified in botanical sources, galantamine used in modern laboratory studies is commonly produced through synthetic methods.

It is important to note that Purerawz only offers Galantamine Hydrobromide as a research chemical intended solely for laboratory use.

Chemical and Molecular Properties

Galantamine Hydrobromide
PubChem CID121587
Molecular FormulaC17H22BrNO3
Molecular Weight368.3 g/mol
SynonymsNivaline 

Nivalin

IUPAC(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol;hydrobromide
CAS1953-04-4
LabelingResearch Use Only (RUO), not for human or animal consumption.
Chemical Structure DepictionScreenshot 2026 03 16 102433
Purity≥98%
ClassificationAcetylcholinesterase inhibitor (research compound)
Storage TemperatureLyophilized at −20 °C; reconstituted solutions at 2–8°C
SolubilitySoluble in water and DMSO
SafetyHandle with gloves, a lab coat, eye protection; use a fume hood if dust/aerosol is possible

Various Mechanisms of Galantamine Hydrobromide

Acetylcholinesterase Inhibition

Galantamine hydrobromide acts as a reversible competitive inhibitor of acetylcholinesterase in experimental systems. Acetylcholinesterase is responsible for hydrolyzing the neurotransmitter acetylcholine within cholinergic synapses.

By inhibiting this enzyme in laboratory models, galantamine allows acetylcholine to persist longer in the synaptic cleft, enabling researchers to investigate the effects of elevated cholinergic signaling in neuronal systems.

Allosteric Modulation of Nicotinic Acetylcholine Receptors

In addition to acetylcholinesterase inhibition, galantamine has been reported to function as a positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs) in experimental models.

Rather than binding to the primary ligand site, the compound interacts with alternative receptor domains that influence receptor conformation. This mechanism can enhance receptor responsiveness to acetylcholine, making galantamine a useful compound for studying receptor-mediated cholinergic signaling pathways in vitro.

Research Applications of Galantamine Hydrobromide

Galantamine hydrobromide is widely used in experimental neuroscience and biochemical research to investigate cholinergic signaling pathways. Common laboratory research applications include:

  • Cholinergic neurotransmission studies
  • Acetylcholinesterase inhibition assays
  • Nicotinic receptor modulation research
  • Neurotransmitter signaling pathway investigations
  • Preclinical models examining cholinergic system dynamics

Why Choose Purerawz for Galantamine Hydrobromide?

Buy Galantamine Hydrobromide for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.

Note:

Galantamine Hydrobromide is an investigational compound currently undergoing clinical evaluation and has not been established as safe or effective for any therapeutic use

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Frequently Asked Questions

What is Galantamine Hydrobromide?

Galantamine Hydrobromide is the hydrobromide salt of galantamine, an alkaloid studied as a cholinergic compound owing to its acetylcholinesterase-inhibiting properties in research models. It is supplied strictly as a research reference material and is not intended for human or veterinary use.

Can Galantamine Hydrobromide be imported or is it legal in Australia?

This compound is provided solely for laboratory research use and is not supplied for human consumption. Cholinergic alkaloids may be subject to import and supply restrictions, so researchers must confirm the current regulatory and import status in their jurisdiction before purchasing.

How is Galantamine Hydrobromide tested?

Identity and purity are confirmed by independent third-party analysis using HPLC and mass spectrometry. A batch-specific certificate of analysis (COA) documenting purity of at least 99% is provided.

How should Galantamine Hydrobromide be stored in the laboratory?

As a salt form it is typically stored as a dry powder in a tightly sealed container, protected from light, heat and moisture. Refer to the certificate of analysis for the recommended storage parameters for each batch.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.

Form

Powder

Strength

500mg

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