Pramiracetam
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Pramiracetam is a synthetic nootropic from the racetam family, originally developed in the 1970s. Unlike many racetams, it is fat-soluble, a property that influences absorption and cellular distribution in laboratory models. This characteristic also allows it to cross cell membranes more efficiently, making it a valuable tool in studies of memory and learning mechanisms.
Pramiracetam is often described as a highly concentrated racetam, meaning smaller amounts are required to produce measurable effects in laboratory research.
Chemical and Molecular Properties
| PubChem CID | 51712 |
| Molecular Formula | C14H27N3O2 |
| Molecular Weight | 269.38 g/mol |
| Synonyms | 68497-62-1 Pramiracetamum N-[2-[bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide 1-Pyrrolidineacetamide, N-(2-(bis(1-methylethyl)amino)ethyl)-2-oxo- CI-879 FREE BASE |
| IUPAC | N-[2-[di(propan-2-yl)amino]ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide |
| CAS | 68497-62-1 |
| Labeling | Research Use Only (RUO), not for human or animal consumption. |
| Chemical Structure Depiction |
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| Purity | 99% Purity |
| Classification | Research Use Only (RUO) |
| Storage Temperature | Room Temperature below 15°C (59°F) |
Mechanisms of Action
The exact mechanism of Pramiracetam is not fully elucidated, but several reproducible effects have been observed in preclinical studies:
- Enhancement of high-affinity choline uptake (HACU)
Research models indicate that Pramiracetam enhances high-affinity choline uptake in the hippocampus. This step regulates acetylcholine production.
- Hippocampal and limbic modulation
Preclinical memory tasks demonstrate that Pramiracetam may reverse experimentally induced amnesia and improve hippocampus-dependent performance.
- Influence on neuronal signaling and local blood flow
Some studies report that Pramiracetam affects nitric oxide synthase signaling and related pathways in brain tissue. This may influence synaptic plasticity and local microcirculation.
Potential Research Applications
Important: The following summaries are provided for research reference only. They do not imply safety, efficacy, or suitability for human use.
- Memory-Related Endpoints: Multiple experimental paradigms, including rodent amnesia models, report improvements in memory performance.
- Reversal of Experimentally Induced Amnesia: In preclinical studies, Pramiracetam has been observed to modulate task performance in laboratory models of experimentally induced amnesia.
- Cognitive Processing in Impaired Models: Certain studies suggest Pramiracetam may enhance attention and cognitive performance in models with prior deficits.
Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use
Frequently Asked Questions
What is Pramiracetam?
Pramiracetam is a lipophilic member of the racetam class, structurally related to piracetam but bearing a dipropan-2-ylamino side chain. It is supplied as a laboratory research reference material and is not intended for human or veterinary use.
Can Pramiracetam be imported or is it legal in Australia?
This compound is offered strictly for laboratory research use only and is not for human consumption. Racetam-class materials may face import and supply restrictions, so researchers are responsible for confirming the current regulatory and import status in their jurisdiction before ordering.
How is Pramiracetam tested?
Each batch undergoes independent third-party testing by HPLC and mass spectrometry to establish identity and purity. A certificate of analysis (COA) confirming at least 99% purity accompanies every batch.
How does Pramiracetam differ from Piracetam in research contexts?
Pramiracetam is notably more lipophilic than piracetam owing to its differing side-chain chemistry, which is often noted in comparative laboratory studies. Researchers frequently reference this structural distinction when characterising the two racetams.
For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.
| Strength | 1.5g, 5g |
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