Ibudilast

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Ibudilast is a small-molecule research compound of the non-selective phosphodiesterase (PDE) inhibitor class, also studied as a glial-cell and macrophage migration inhibitory factor (MIF) modulator. It is supplied strictly for laboratory research use only and is not intended for human or veterinary use. Ibudilast is widely used by laboratory researchers as a reference material in neuroinflammation and glial-signalling investigations.

Research Background

Ibudilast has been investigated in research on inhibition of several phosphodiesterase isoenzymes, including PDE-4 and PDE-10, and on the suppression of pro-inflammatory glial activation. Preclinical studies have examined its interaction with macrophage migration inhibitory factor and its influence on cytokine signalling in cell-culture and rodent models of neuroinflammation.

The compound is frequently referenced in exploratory work concerning the crosstalk between cyclic nucleotide signalling and neuroimmune pathways. This material is offered only as a characterised laboratory standard to support such in vitro and preclinical research, and no applied or clinical inference should be drawn from its listing here.

Ibudilast Specifications & Handling

Purity: ≥99% as determined by analytical assay.
Third-party verification: independent HPLC and mass spectrometry, with a batch-specific Certificate of Analysis (COA) available.
Physical form: powder.
Storage: store in a cool, dry, dark environment; keep sealed and protected from light and moisture.
Intended use: in vitro and preclinical laboratory research reference applications only.

Related Research Compounds

Laboratories studying neuroimmune and glial signalling frequently pair Ibudilast with standards such as Methylene Blue, NSI-189 Phosphate and Vinpocetine. The full selection of reference materials is available in the research nootropics catalogue.

Frequently Asked Questions

What is Ibudilast?

Ibudilast is a non-selective phosphodiesterase inhibitor and glial modulator studied in neuroinflammation research. It is supplied purely as a reference material for laboratory use.

Is Ibudilast permitted for research import and use in Australia?

It is supplied for laboratory research use only and not for human or veterinary use. Australian researchers are responsible for verifying the current regulatory, import and supply status of this compound in their jurisdiction before purchase.

How is Ibudilast tested for purity?

Every batch is analysed by independent HPLC and mass spectrometry, and a batch-specific Certificate of Analysis can be provided on request.

What are the recommended storage conditions for Ibudilast?

Store the powder sealed in a cool, dry and dark environment, protected from light and moisture, to maintain its integrity throughout the research period.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.