Sunifiram

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    To maintain the highest standards of analytical transparency and product safety, we do not accept returns. We are committed to accurate order fulfillment and support; please contact our team prior to purchasing if you have questions regarding specifications.While we do not accept returns on research compounds, if you receive an incorrect item or your package arrives damaged, please contact our support team within 48 hours of delivery for a prompt resolution.

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Buy Sunifiram online | Sunifiram for sale

Sunifiram is an Ampakine drug (acts via AMPA receptors). It is a synthetic derivative of Piracetam and has a somewhat similar chemical structure. Still, despite having comparable anti-amnesic effects, Sunifiram demonstrates significantly higher potency than piracetam in preclinical models.

Sunifiram was originally developed to treat the symptoms of cognitive decline in Alzheimer’s disease patients. However, due to the lack of funding, no human trials were conducted to investigate its effects. All the evidence about its effects comes from animal studies.

Furthermore, it has been reported that Sunifiram attenuates experimentally induced memory deficits in research models. It alleviates cognitive deficits and possesses potent anti-amnesic activity in preclinical models. Preclinical research has also demonstrated that Sunifiram may have mild effects on nociceptive responses in research models.

Note: PureRawz sells Sunifiram for laboratory and research purposes only.

Chemical Properties of Sunifiram

PropertyInformation
CAS Number314728-85-3
IUPAC Name1-(4-benzoylpiperazin-1-yl)propan-1-one
Chemical FormulaC14H18N2O2
Molecular Weight246.31 g/mol
SynonymsSUNIFIRAM, DM-235, DM235, DTXSID10400996, Sunifiram DM235
Storage-20°C (-4°F)

Working Mechanism of Sunifiram?

The exact working mechanism of Sunifiram remains unknown, but it has been shown to:

Stimulate the release of acetylcholine

In one animal study, Sunifiram reportedly increased acetylcholine release. Another preclinical study showed it blocked the effects of scopolamine, a drug that blocks acetylcholine release.

Activate AMPA receptors

Study reports suggest that unifiram appears to modulate glutamatergic signaling involving NMDA and AMPA receptor pathways. Plus, it may block AMPA receptor activation by drugs that suppress the activity of AMPA receptors.

Regulate glucose uptake

A cell-based study reports that Sunifiram may increase glucose uptake at a lower dose and increase it at a mega dose.

Activate NDMA glutamate receptors.

Another cell-based study suggests how Sunifiram may activate NDMA glutamate receptors. That is, by promoting the release of the neurotransmitter glutamate, which is proven to bind to glutamate receptors.

Research findings on Sunifiram

The following is a summary of the existing research on Sunifiram. The information given in this section is for educational purposes only and doesn’t constitute medical advice.

Experimental studies have investigated Sunifiram for its effects on memory-related processes. Some preclinical research models reported that Sunifiram partially reversed induced memory impairments and influenced Long-Term Potentiation (LTP). LPT is a mechanism involved in synaptic plasticity and memory formation.

Research has also examined Sunifiram in behavioral learning tasks. In research models, exposure to Sunifiram was linked with improved performance in tasks that measure learning and recognition, including passive avoidance and social recognition tests. These findings suggest possible interactions with neural pathways related to learning processes.

A few studies have reported additional neurological effects of Sunifiram. Some experimental findings report mild effects on heat-related pain responses and changes in sleep-related behavior in research models. These observations remain preliminary and require further investigation in laboratory studies.

Where to Buy Sunifiram?

PureRawz is the best place to buy the highest-quality Sunifiram online.

In order to be the best supplier of research chemicals, we provide reference materials with every product we sell. All of our products come with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

We sell Sunifiram powder and tablet formulations for laboratory and research purposes only.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.

Frequently Asked Questions

What is Sunifiram?

Sunifiram (DM-235) is a synthetic piperazine-based compound and a ring-opened analogue of unifiram, studied within the ampakine-adjacent research family. It is supplied strictly as a research chemical for laboratory investigation and is not for human or veterinary use.

Can Sunifiram be imported or is it legal in Australia?

Sunifiram is offered for laboratory research use only, and novel synthetic compounds in this class may face import or supply restrictions in Australia. Researchers must confirm the current regulatory and import status with the relevant authorities before ordering or importing.

How is Sunifiram tested?

Each batch is analysed by independent third-party laboratories using high-performance liquid chromatography (HPLC) and mass spectrometry. A batch-specific certificate of analysis (COA) documents identity and a purity specification of not less than 99%.

How does Sunifiram compare with Unifiram as a research reference?

Sunifiram is a ring-opened structural analogue of unifiram, so the two share a related scaffold but differ in ring configuration. Both are used as reference materials in laboratory research and are not intended for any human application.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.

Form

Tablets, Powder

Strength

80mg per tablet/35ct/2.8g, 80mg per tablet/70ct/5.6g, 5g

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