Pterostilbene (Dimethylresveratrol)
AUD30
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Pterostilbene (Dimethylresveratrol) is a naturally occurring polyphenolic stilbene compound found at low concentrations in certain plant species, including blueberries (Vaccinium spp.), grapes (Vitis spp.), and select tree barks. Structurally, it is a dimethylated analog of resveratrol, with two methoxy groups replacing hydroxyl groups, which has led researchers to study its in vitro and preclinical properties related to intracellular signaling, antioxidant capacity, and metabolic regulation.
It is important to note that Purerawz only offers Pterostilbene as a research chemical intended solely for laboratory use.
Chemical and Molecular Properties
| Pterostilbene (Dimethylresveratrol) | |
| PubChem CID | 5281727 |
| Molecular Formula | C16H16O3 |
| Synonyms | trans-pterostilbene 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol pterostilbene, (E)- |
| Molecular Weight | 256.30 g/mol |
| IUPAC | 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol |
| Chemical Structure Depiction |  |
| CAS | 537-42-8 |
| Storage Temperature | 2–8°C (refrigerated, protected from light) |
| Solubility | Insoluble in water; soluble in DMSO |
Mechanism of Action
In experimental in vitro and preclinical models, pterostilbene has been associated with several intracellular responses:
Activation of SIRT1 in Experimental Models
Pterostilbene has been reported to modulate sirtuin–1 (SIRT1) activity in laboratory studies. SIRT1 is a class III histone deacetylase linked to the regulation of cellular stress response and energy metabolism. In research contexts, compounds that engage SIRT1 are used to explore gene expression profiles influenced by deacetylation pathways.
Antioxidant Activity
As a polyphenolic stilbene, pterostilbene exhibits ROS–scavenging activity in cellular assays, which is used to investigate mechanisms of redox homeostasis and oxidative damage in cultured cells. These antioxidant effects are examined in biochemical studies to assess interactions with reactive oxygen species and cellular defense mechanisms.
Modulation of AMPK Pathway
In laboratory models, pterostilbene has been shown to interact with the AMP–activated protein kinase (AMPK) signaling network. AMPK functions as a cellular energy sensor, and its activation in research settings is associated with studies of metabolic regulation and bioenergetic homeostasis.
Anti–Inflammatory Actions in Research Settings
Pterostilbene has been observed to influence inflammatory signaling pathways in in vitro systems, including modulation of NF‑κB activation and downstream cytokine expression. These responses are investigated to improve understanding of inflammatory mediator regulation.
Research Applications of Pterostilbene
Pterostilbene is employed across various experimental models to investigate cellular signaling and biochemical processes:
- Cellular Oxidative Stress Studies
- Inflammatory Pathway Analysis
- Energy Metabolism and AMPK Signaling Research
- Sirtuin Regulation Studies
Why Choose PureRawz for Pterostilbene (Dimethylresveratrol)?
Buy Pterostilbene (Dimethylresveratrol) for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.
Note:
Pterostilbene (Dimethylresveratrol) is an investigational compound currently undergoing clinical evaluation and has not been established as safe or effective for any therapeutic use.
Disclaimer
This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.
ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use.
Frequently Asked Questions
What is Pterostilbene (Dimethylresveratrol)?
Pterostilbene is a naturally occurring stilbenoid compound and a dimethylated analogue of resveratrol, belonging to the polyphenol class. It is supplied strictly as a research chemical for laboratory investigation and is not for human or veterinary use.
Can Pterostilbene be imported or is it legal in Australia?
Pterostilbene is offered for laboratory research use only, and some compounds in this class may be subject to import or supply conditions in Australia. Researchers must verify the current regulatory and import status with the relevant authorities before ordering or importing.
How is Pterostilbene tested?
Each batch is analysed by independent third-party laboratories using high-performance liquid chromatography (HPLC) and mass spectrometry. A batch-specific certificate of analysis (COA) documents identity and a purity specification of not less than 99%.
How does Pterostilbene compare with resveratrol as a research reference?
Pterostilbene differs structurally from resveratrol by two methoxy groups in place of hydroxyl groups, a modification often studied in relation to lipophilicity and metabolic stability. Both are polyphenolic stilbenes used as reference materials in laboratory research.
For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.
| Form | Powder |
|---|---|
| Strength | 10g |
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