L-Theanine

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L-theanine is a naturally occurring amino acid found mainly in green tea leaves. It is studied for its effects on neural activity, stress-related pathways, and cognitive function in experimental models.

Researchers investigate L-theanine for its ability to influence neurotransmitters such as GABA and dopamine.

Note: This description refers to research-grade L-theanine, which is not intended for human or veterinary use

Chemical Properties

Chemical Name	L-Theanine (Y-glutamylethylamide)
CAS Number	3081-61-6
Chemical Formula	C7H14N2O3
Molar Mass	174.200 g/mol
Appearance	White, odorless, crystalline powder
Stability	Stable under normal conditions
Solubility	Insoluble in ethanol, Soluble in Water
Other Name	N5-ethyl-L-glutamine, L-gamma-glutamylethylamide

What is the mechanism of action of L-theanine?

Preclinical and exploratory studies suggest, L-theanine follows this mechanism of action:

L-theanine is structurally similar to glutamine and may act as a glutamate analog in certain pathways.
L-theanine is observed in preclinical studies to influence the levels of neurotransmitters such as GABA, serotonin, and dopamine. It may also modulate neural activity associated with relaxation in experimental models.
It may modulate alpha-wave activity in electrophysiological studies.

What are the potential benefits of L-theanine?

In experimental studies, researchers have observed the following potential effects:

It may help manage stress without causing sedation in research models.
It may increase cognitive performance measures such as memory and attentional processing when studied in combination with caffeine in experimental models
It is studied for its effects on sleep-related neurotransmitters in research models. It may modulate neurotransmitters such as GABA, serotonin, dopamine, and glutamate in research models.
In some preclinical models, L-theanine has demonstrated antioxidant-like effects.
Studies suggest L-theanine may interact with compounds such as caffeine to influence cognitive results in experimental models.

Research on L-theanine

Research suggests its role in immune modulation, brain function, and potential anti-inflammatory pathways in preclinical models.
Research also focuses on its impact in animal models, where it may regulate cytokine production and immune balance.
Preclinical studies also focused on its impact on neurotransmitter levels such as Serotonin, GABA, and Glutamate.
Some exploratory clinical studies have investigated its effects on sleep quality and verbal fluency.

What is the best place to buy L-theanine online for research purposes?

PureRawz is a reliable source to buy research-grade L-theanine online. They provide reference materials with every product they sell. Each of their products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

They offer free international shipping on all orders above $100. You can pay for your purchase through various methods, including PayPal and Bitcoin.

Note:In the Nootropics Powder category, PureRawz offers lab-tested formulations including IDRA-21, Myo-Inositol Trispyrophosphate (ITPP) and many other product.

Is L-theanine Legal?

L-theanine holds the FDA’s GRAS (Generally Recognized as Safe) designation for use in foods and dietary supplements. However, research-grade L-theanine is sold for laboratory and scientific use.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions.

Frequently Asked Questions

What is L-Theanine?

L-Theanine is an amino acid analogue of glutamate found naturally in tea leaves, belonging to the amino acid class of compounds. It is supplied strictly as a research chemical for laboratory investigation and is not for human or veterinary use.

Can L-Theanine be imported or is it legal in Australia?

L-Theanine is offered for laboratory research use only, and some compounds in this class may be subject to import or supply conditions in Australia. Researchers must verify the current regulatory and import status with the relevant authorities before ordering or importing.

How is L-Theanine tested?

Each batch is analysed by independent third-party laboratories using high-performance liquid chromatography (HPLC) and mass spectrometry. A batch-specific certificate of analysis (COA) documents identity and a purity specification of not less than 99%.

How does L-Theanine compare with L-Carnosine as a research reference?

L-Theanine is a single amino acid analogue, whereas L-Carnosine is a dipeptide formed from two amino acids, so they differ in structure and molecular weight. Both are used as reference materials in laboratory research.

For laboratory and research use only. This product is not for human or veterinary consumption, and nothing on this page is medical advice. Researchers are responsible for compliance with all applicable Australian laws (including TGA regulations) and institutional guidelines.